By contrast, DFT2 emerged in 2011 and the first case was detected in a male devil three years later.
This female demon is believed to have been a superspreader who passed her tumour cells to at least six other demons, leading to the emergence of six major DFT1 variants. The results reveal that DFT1, which has spread across most of Tasmania, emerged in 1986 and the first case was detected in a female devil around a decade later. A team of scientists led by disease ecologist Rodrigo Hamede of the University of Tasmania in Hobart have assembled a reference Tasmanian devil genome and compared it to DNA sequenced from 78 DFT1 and 41 DFT2 tumours to investigate their origins and mutations. Although researchers have known about these cancers, little has been known about their evolution.
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